Anti-Prostaglandin D2 Receptor antibody (ab77650)

Overview

  • Product nameAnti-Prostaglandin D2 Receptor antibody
    See all Prostaglandin D2 Receptor primary antibodies
  • Description
    Rabbit polyclonal to Prostaglandin D2 Receptor
  • Specificityab77650 detects endogenous levels of total Prostaglandin D2 Receptor protein.
  • Tested applicationsSuitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence within human Prostaglandin D2 Receptor.

  • Positive control
    • HepG2 cell extracts; A549 cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab77650 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab77650 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
ELISA 1/40000.
ICC/IF 1/500 - 1/1000.

Target

  • FunctionReceptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate.
  • Tissue specificityExpressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
  • Involvement in diseaseGenetic variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1) [MIM:607277]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AS 1 antibody
    • AS1 antibody
    • ASRT 1 antibody
    • ASRT1 antibody
    • DP antibody
    • MGC49004 antibody
    • OTTHUMP00000178986 antibody
    • PD2R_HUMAN antibody
    • PGD receptor antibody
    • PGD2 receptor antibody
    • Prostaglandin D2 receptor (DP) antibody
    • Prostaglandin D2 receptor antibody
    • Prostanoid DP receptor antibody
    • Ptgdr antibody
    see all

Anti-Prostaglandin D2 Receptor antibody images

  • ab77650 at 1/500 dilution staining Prostaglandin D2 Receptor in A549 cells by Immunofluorescence, in the absence or presence of the immunising peptide.
  • All lanes : Anti-Prostaglandin D2 Receptor antibody (ab77650) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : HepG2 cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Prostaglandin D2 Receptor antibody (ab77650)

ab77650 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"