Anti-Prostaglandin E Receptor EP2 antibody (ab124419)

Overview

  • Product name
    Anti-Prostaglandin E Receptor EP2 antibody
    See all Prostaglandin E Receptor EP2 primary antibodies
  • Description
    Rabbit polyclonal to Prostaglandin E Receptor EP2
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to a region from the C-terminus of Human Prostaglandin E Receptor EP2.

  • Positive control
    • Mouse liver cell extract, Human Uterus, Myometrium tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab124419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 40 kDa.
ELISA 1/1000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
  • Tissue specificity
    Placenta and lung.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EP2 antibody
    • PE2R2_HUMAN antibody
    • PGE receptor EP2 subtype antibody
    • PGE2 receptor EP2 subtype antibody
    • Prostaglandin E receptor 2 EP2 subtype antibody
    • Prostaglandin E receptor 2 subtype EP2 53kDa antibody
    • Prostaglandin E receptor 2 subtype EP2 antibody
    • Prostaglandin E2 receptor antibody
    • Prostaglandin E2 receptor EP2 subtype antibody
    • Prostanoid EP2 receptor antibody
    • Ptger2 antibody
    see all

Images

  • All lanes : Anti-Prostaglandin E Receptor EP2 antibody (ab124419) at 1/500 dilution

    Lane 1 : Mouse liver cell extract
    Lane 2 : Mouse liver cell extract with synthesized peptide


    Predicted band size : 40 kDa
  • Staining of Prostaglandin E Receptor EP2 in Paraffin-embedded Human Uterus, Myometrium tissue by Immunohistochemistry using ab124419 at a concentration of 5 µg/ml.

References

This product has been referenced in:
  • Mochocki M  et al. Expression of prostaglandin E2 prostanoid receptor EP2 and interleukin-1ß in laryngeal carcinoma - preliminary study. Contemp Oncol (Pozn) 19:113-9 (2015). IHC-P ; Human . Read more (PubMed: 26034388) »
  • Kaul V  et al. Prostanoid receptor 2 signaling protects T helper 2 cells from BALB/c mice against activation-induced cell death. J Biol Chem 287:25434-9 (2012). WB ; Mouse . Read more (PubMed: 22654101) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you for your inquiry.

The lab that tested this antibody and produced the image (human formalin-fixed paraffin-embedded tissues)on the datasheet as result used the following antigen retrieval method:

1.) Steam slides in 0.01 M ...

Read More

To our knowledge, the antibody ab124419 has not been published, but the in-house western blot and IHC data are very clean.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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