Prostaglandin E Receptor EP4 peptide (302-314) (ab45876)

Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-LEREVSKNPDLQA
    • Amino acids
      302 to 314

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Prostaglandin E Receptor EP4 antibody (ab45863)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • EP 4
    • EP4
    • EP4R
    • MGC126583
    • PE2R4_HUMAN
    • PGE receptor EP4 subtype
    • PGE2 receptor EP4 subtype
    • Prostaglandin E receptor 4
    • Prostaglandin E receptor 4 subtype EP4
    • Prostaglandin E2 receptor
    • Prostaglandin E2 receptor EP4 subtype
    • Prostanoid EP4 receptor
    • PTGER 2
    • PTGER 4
    • PTGER2
    • PTGER4
    see all
  • Function
    Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
  • Tissue specificity
    High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab45876 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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