Overview

  • Product nameProstaglandin H2
  • Description
    Major prostanoid; important precursor in eicosanoid synthesis
  • Alternative names
    • PGH2
  • Biological descriptionMajor prostanoid; important precursor in eicosanoid synthesis. Formed following catalysis of arachidonic acid (AA) by COX and is subsequently converted by cell-specific synthases to form biologically active PGs and thromboxane.
  • Purity> 95%

Properties

  • Chemical name(5Z,9α,11α,13E,15S)-9,11-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid
  • Molecular weight352.47
  • Chemical structureChemical Structure
  • Molecular formulaC20H32O5
  • CAS Number42935-17-1
  • Storage instructionsStore at -80°C.
  • Solubility overviewSupplied in acetone (100 µg/ml)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESCCCCC[C@@H](O)/C=C/[C@H]1[C@@H]2OO[C@@H](C2)[C@H]1C/C=CCCCC(O)=O
  • Source

    Synthetic

  • Research areas

    References for Prostaglandin H2 (ab120910)

    This product has been referenced in:
    • Malhotra S  et al. COX inhibitors for airway inflammation. Expert Opin Ther Targets 16:195-207 (2012). Read more (PubMed: 22324934) »
    • Lin L  et al. Expression of prostaglandin H2-mediated mechanism of vascular contraction in hypertensive rats. Relation to lipoxygenase and prostacyclin synthase activities. Circ Res 74:197-205 (1994). Read more (PubMed: 8293559) »
    • Gorman RR  et al. Inhibition of basal and hormone-stimulated adenylate cyclase in adipocyte ghosts by the prostaglandin endoperoxide prostaglandin H2. J Biol Chem 250:6460-3 (1975). Read more (PubMed: 169245) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120910.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"