Biological descriptionPKC activator; reactivates HIV-1 latency (IC50 = ~0.5 µM) by PKC dependent NF-κB activation. Downregulates expression of HIV-1 receptor CD4 and its co-receptors CXCR4 and CCR5 in vitro. Non-tumor promoting.
Storage instructionsStore at -20°C (desiccating conditions).
Supplied in ethanol (at lot-dependent concentrations). Soluble in ethanol to 10 mg/ml.
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.