Anti-Proteasome 19S S5A antibody (ab3318)

Overview

  • Product nameAnti-Proteasome 19S S5A antibody
    See all Proteasome 19S S5A primary antibodies
  • Description
    Rabbit polyclonal to Proteasome 19S S5A
  • SpecificityDetects proteasome 19S subunit S5A.
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Other Immunogen Type corresponding to Human Proteasome 19S S5A. Human recombinant proteasome 19S subunit S5A.

  • Positive control
    • HeLa cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferConstituents: 0.1% BSA, 99% PBS
  • Concentration information loading...
  • PurityIgG fraction
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab3318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 50 kDa (predicted molecular weight: 40 kDa).

By Western blot, this antibody detects a 50 kDa protein representing proteasome 19S subunit S5A in HeLa cell lysate.

IP Use at an assay dependent concentration.

Target

  • FunctionBinds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.
  • Sequence similaritiesBelongs to the proteasome subunit S5A family.
    Contains 2 UIM (ubiquitin-interacting motif) repeats.
    Contains 1 VWFA domain.
  • DomainThe 2 UIM motifs are involved in the binding to a multi-ubiquitin chain in a cooperative way.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links
  • Alternative names
    • 26S protease subunit S5a antibody
    • 26S proteasome non ATPase regulatory subunit 4 antibody
    • 26S proteasome non-ATPase regulatory subunit 4 antibody
    • 26S proteasome regulatory subunit rpn10 antibody
    • 26S proteasome regulatory subunit S5A antibody
    • AF 1 antibody
    • AF antibody
    • AF1 antibody
    • Angiocidin antibody
    • Antisecretory factor 1 antibody
    • ASF antibody
    • DS5a antibody
    • MCB 1 antibody
    • MCB1 antibody
    • Multiubiquitin chain binding protein antibody
    • Multiubiquitin chain-binding protein antibody
    • OTTHUMP00000059963 antibody
    • Prosome macropain antibody
    • Proteasome (prosome macropain) 26S subunit non ATPase 4 antibody
    • Proteasome 26S non ATPase subunit 4 antibody
    • Proteasome 26S subunit non ATPase 4 antibody
    • PSMD 4 antibody
    • Psmd4 antibody
    • PSMD4_HUMAN antibody
    • pUB R5 antibody
    • pUBR5 antibody
    • Rpn 10 antibody
    • Rpn10 antibody
    • RPN10 homolog antibody
    • S5A antibody
    • S5a/antisecretory factor protein antibody
    see all

Anti-Proteasome 19S S5A antibody images



  • Predicted band size : 40 kDa

    Western blot of proteasome 19S subunit S5A on HeLa cell lysate using ab3318.

References for Anti-Proteasome 19S S5A antibody (ab3318)

ab3318 has not yet been referenced specifically in any publications.

Product Wall

Regarding your inquiry, this product anti-Proteasome 19S S5A antibody (ab3318) was created against recombinant human proteasome 19S subunit S5A (http://www.expasy.org/uniprot/P55036). The sequence for this protein is: 10 20 ...

Read More

Thank you for your enquiry regarding ab3318. This antibody is a rabbit polyclonal antibody raised against the human recombinant full length proteasome 19S S5A protein. It will therefore recognise multiple epitopes on the protein. The antibody is th...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"