Anti-Proteasome 20S alpha 3 antibody (ab96746)

Overview

  • Product name
    Anti-Proteasome 20S alpha 3 antibody
    See all Proteasome 20S alpha 3 primary antibodies
  • Description
    Rabbit polyclonal to Proteasome 20S alpha 3
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Zebrafish
  • Immunogen

    Recombinant fragment corresponding to Human Proteasome 20S alpha 3 aa 1-147.
    Database link: P25788

  • Positive control
    • MOLT4 whole cell lysate; U87 xenograft; Raji cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab96746 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
  • Sequence similarities
    Belongs to the peptidase T1A family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HC8 antibody
    • Macropain subunit C8 antibody
    • MGC12306 antibody
    • MGC32631 antibody
    • Multicatalytic endopeptidase complex subunit C8 antibody
    • Proteasome (prosome macropain) subunit alpha type 3 antibody
    • Proteasome alpha 3 subunit antibody
    • Proteasome component C8 antibody
    • Proteasome subunit alpha type 3 antibody
    • Proteasome subunit alpha type-3 antibody
    • Proteasome subunit C8 antibody
    • PSA3_HUMAN antibody
    • PSC8 antibody
    • psmA3 antibody
    see all

Images

  • Anti-Proteasome 20S alpha 3 antibody (ab96746) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

    Predicted band size : 28 kDa
  • ab96746, at 1/100 dilution, staining Proteasome 20S alpha 3 in paraffin-embedded U87 xenograft by Immunohistochemistry.

References

ab96746 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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