Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Accession
    • Sequence
      PLEIEVLEET VQTMDTS
    • Amino acids
      263 to 277

Associated products

Specifications

Our Abpromise guarantee covers the use of ab4948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human proteasome 20S beta 7, catalog ab3332. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names
    • Macropain chain Z
    • Multicatalytic endopeptidase complex chain Z
    • Proteasome (prosome macropain) subunit beta type 7
    • Proteasome beta 7 subunit
    • Proteasome catalytic subunit 2
    • Proteasome subunit alpha
    • Proteasome subunit beta 7
    • Proteasome subunit beta type-7
    • Proteasome subunit Z
    • PSB7_HUMAN
    • PSMB7
    • PUP1
    • Z
    see all
  • Function
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity.
  • Tissue specificity
    Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
  • Sequence similarities
    Belongs to the peptidase T1B family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab4948 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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