Overview

  • Product name
    Anti-Proteasome 26S S2 antibody
    See all Proteasome 26S S2 primary antibodies
  • Description
    Rabbit polyclonal to Proteasome 26S S2
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Xenopus laevis, Zebrafish
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 504-746 of the Human Proteasome 26S S2 protein (Q13200).

  • Positive control
    • 293T, A431 and Raji cell lysates and Human A431 cells.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.58% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab125914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 100 kDa.
ICC/IF 1/100 - 1/500.

Target

  • Function
    Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
    Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
  • Tissue specificity
    Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.
  • Sequence similarities
    Belongs to the proteasome subunit S2 family.
    Contains 7 PC repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • 26S proteasome non-ATPase regulatory subunit 2 antibody
    • 26S proteasome regulatory subunit RPN1 antibody
    • 26S proteasome regulatory subunit S2 antibody
    • 26S proteasome subunit p97 antibody
    • 55.11 protein antibody
    • MGC14274 antibody
    • P97 antibody
    • Proteasome (prosome macropain) 26S subunit non ATPase 2 antibody
    • Proteasome 26S subunit, non-ATPase, 2 antibody
    • Proteasome 26S, subunit 2 antibody
    • Protein 55.11 antibody
    • Psmd2 antibody
    • PSMD2_HUMAN antibody
    • Rpn1 antibody
    • S2 antibody
    • TNFR associated protein 2 antibody
    • TRAP2 antibody
    • Tumor necrosis factor receptor associated protein 2 antibody
    • Tumor necrosis factor type 1 receptor-associated protein 2 antibody
    see all

Images

  • ab125914, at 1/500, staining Proteasome 26S S2 antibody in Human A431 cells by Immunofluorescence (methanol-fixed).
  • Anti-Proteasome 26S S2 antibody (ab125914) at 1/500 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 100 kDa

References

ab125914 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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