Overview

  • Product name
    Anti-Proteasome 26S S5 antibody
    See all Proteasome 26S S5 primary antibodies
  • Description
    Rabbit polyclonal to Proteasome 26S S5
  • Specificity
    Detects purified human proteasome 26S subunit S5b.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow, Cynomolgus monkey
  • Immunogen

    Synthetic peptide corresponding to Human Proteasome 26S S5 aa 485-504.
    Sequence:

    LSEGPYYVKPVSTTAVEGAE

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Constituents: 0.1% BSA, 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab3319 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 56 kDa).

Target

  • Function
    Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
  • Sequence similarities
    Belongs to the proteasome subunit S5B/HSM3 family.
  • Domain
    Rich in dileucine repeats, which have been implicated in trafficking of a variety of transmembrane proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • 26S protease subunit S5 basic antibody
    • 26S proteasome non-ATPase regulatory subunit 5 antibody
    • 26S proteasome subunit S5B antibody
    • Protease 26S, subunit 5B antibody
    • Proteasome (prosome, macropain) 26S subunit, non ATPase, 5 antibody
    • Proteasome 19S S5B antibody
    • Proteasome 26S subunit, non ATPase, 5 antibody
    • PSMD5 antibody
    • PSMD5_HUMAN antibody
    • S5B antibody
    see all

Images



  • Predicted band size : 56 kDa

    Western blot of proteasome 26S subunit S5b on purified 26S proteasome using ab3319.

References

ab3319 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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