Anti-Proteasome 26S S5 antibody - C-terminal (ab156233)

Overview

  • Product name
    Anti-Proteasome 26S S5 antibody - C-terminal
    See all Proteasome 26S S5 primary antibodies
  • Description
    Rabbit polyclonal to Proteasome 26S S5 - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 428-457 of Human Proteasome 26S S5 (NP_005038.1).

  • Positive control
    • HepG2 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab156233 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab156233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.

Target

  • Function
    Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
  • Sequence similarities
    Belongs to the proteasome subunit S5B/HSM3 family.
  • Domain
    Rich in dileucine repeats, which have been implicated in trafficking of a variety of transmembrane proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • 26S protease subunit S5 basic antibody
    • 26S proteasome non-ATPase regulatory subunit 5 antibody
    • 26S proteasome subunit S5B antibody
    • Protease 26S, subunit 5B antibody
    • Proteasome (prosome, macropain) 26S subunit, non ATPase, 5 antibody
    • Proteasome 19S S5B antibody
    • Proteasome 26S subunit, non ATPase, 5 antibody
    • PSMD5 antibody
    • PSMD5_HUMAN antibody
    • S5B antibody
    see all

Images

  • Anti-Proteasome 26S S5 antibody - C-terminal (ab156233) at 1/100 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 56 kDa

References

ab156233 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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