Anti-Proteasome subunit beta type 4 antibody (ab115026)

Overview

  • Product nameAnti-Proteasome subunit beta type 4 antibody
    See all Proteasome subunit beta type 4 primary antibodies
  • Description
    Goat polyclonal to Proteasome subunit beta type 4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Cow, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to Human Proteasome subunit beta type 4 aa 233-243 (internal sequence).
    Sequence:

    C-QIATVTEKGVE


    Database link: P28070

  • Positive control
    • NIH3T3, HEK293, HeLa, Jurkat and K562 cell line lysates.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab115026 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab115026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).

Target

  • FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
  • Sequence similaritiesBelongs to the peptidase T1B family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 26 kDa prosomal protein antibody
    • HN3 antibody
    • HsBPROS26 antibody
    • HSN3 antibody
    • Macropain beta chain antibody
    • Multicatalytic endopeptidase complex beta chain antibody
    • PROS-26 antibody
    • PROS26 antibody
    • Proteasome (prosome macropain) subunit beta type 4 antibody
    • Proteasome beta 4 subunit antibody
    • Proteasome beta chain antibody
    • Proteasome chain 3 antibody
    • Proteasome subunit beta type 4 antibody
    • Proteasome subunit beta type-4 antibody
    • Proteasome subunit HsN3 antibody
    • PSB4_HUMAN antibody
    • PSMB 4 antibody
    • PSMB4 antibody
    see all

Anti-Proteasome subunit beta type 4 antibody images

  • Anti-Proteasome subunit beta type 4 antibody (ab115026) at 0.3 µg/ml + HEK293 cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 25 kDa

References for Anti-Proteasome subunit beta type 4 antibody (ab115026)

ab115026 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"