Overview

  • Product nameAnti-Protein Kinase D2 antibody
    See all Protein Kinase D2 primary antibodies
  • Description
    Rabbit polyclonal to Protein Kinase D2
  • Specificityab118639 detects endogenous levels of total Protein Kinase D2 protein.
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide conjugated to KLH, from the C terminus of Human Protein Kinase D2 (NP_057541.2).

  • Positive control
    • Human Heart, Human Brain Cerebellum and Human Intestine tissues. NIH 3T3 cell extracts.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS without Mg2+, Ca2+
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 97 kDa.
ELISA 1/5000.
IHC-P Use a concentration of 10 µg/ml.

Target

  • FunctionConverts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
    Contains 1 PH domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylation of Ser-876 correlates with the activation status of the kinase.
    Ser-706 is probably phosphorylated by PKC.
  • Cellular localizationCytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp586E0820 antibody
    • HSPC187 antibody
    • KPCD2_HUMAN antibody
    • nPKC D2 antibody
    • nPKC-D2 antibody
    • PKD2 antibody
    • PRKD 2 antibody
    • Prkd2 antibody
    • Protein kinase D2 antibody
    • Serine/threonine protein kinase D2 antibody
    • Serine/threonine-protein kinase D2 antibody
    see all

Anti-Protein Kinase D2 antibody images

  • ab118639 at 10 µg/ml staining Protein Kinase D2 in Formalin-Fixed, Paraffin-Embedded Human Brain Cerebellum tissue by Immunohistochemistry.
  • ab118639 at 10 µg/ml staining Protein Kinase D2 in Formalin-Fixed, Paraffin-Embedded Human Heart tissue by Immunohistochemistry.
  • ab118639 at 10 µg/ml staining Protein Kinase D2 in Formalin-Fixed, Paraffin-Embedded Human Intestine tissue by Immunohistochemistry.
  • All lanes : Anti-Protein Kinase D2 antibody (ab118639) at 1/500 dilution

    Lane 1 : NIH 3T3 cell extract, treated with PMA 250ng/ml for 15 mins.
    Lane 2 : NIH 3T3 cell extract, treated with PMA 250ng/ml for 15 mins with synthesized peptide


    Predicted band size : 97 kDa

References for Anti-Protein Kinase D2 antibody (ab118639)

ab118639 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"