Anti-Protein phosphatase 1 inhibitor 3C antibody (ab103299)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab103299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 36 kDa.

Target

  • FunctionActs as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
  • Sequence similaritiesContains 1 CBM21 (carbohydrate binding type-21) domain.
  • DomainThe N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase, glycogen synthase and phosphorylase kinase.
  • Post-translational
    modifications
    Ubiquitinated by NHLRC1/malin in a EPM2A/laforin-dependent manner.
  • Information by UniProt
  • Database links
  • Alternative names
    • OTTHUMP00000020089 antibody
    • Phosphatase 1, regulatory inhibitor subunit 5 antibody
    • PP1 subunit R5 antibody
    • ppp1r3c antibody
    • PPP1R5 antibody
    • PPR3C_HUMAN antibody
    • Protein phosphatase 1 regulatory subunit 3C antibody
    • Protein phosphatase 1 regulatory subunit 5 antibody
    • protein phosphatase 1, regulatory (inhibitor) subunit 3C antibody
    • Protein targeting to glycogen antibody
    • PTG antibody
    • R5 antibody
    see all

Anti-Protein phosphatase 1 inhibitor 3C antibody images

  • Anti-Protein phosphatase 1 inhibitor 3C antibody (ab103299) at 5 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 36 kDa
  • All lanes : Anti-Protein phosphatase 1 inhibitor 3C antibody (ab103299) at 5 µg/ml

    Lane 1 : Protein phosphatase 1 inhibitor 3C transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 36 kDa

References for Anti-Protein phosphatase 1 inhibitor 3C antibody (ab103299)

ab103299 has not yet been referenced specifically in any publications.

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