Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab66068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

Target

  • FunctionReceptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
  • Tissue specificityHighest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • coagulation factor II (thrombin) receptor-like 2 antibody
    • Coagulation factor II receptor-like 2 antibody
    • F2RL2 antibody
    • PAR 3 antibody
    • PAR-3 antibody
    • PAR3 antibody
    • PAR3_HUMAN antibody
    • protease activated receptor 3 antibody
    • Proteinase-activated receptor 3 antibody
    • thrombin receptor like 2 antibody
    • Thrombin receptor-like 2 antibody
    see all

Anti-Proteinase Activated Receptor 3 antibody images

  • Anti-Proteinase Activated Receptor 3 antibody (ab66068) at 1 µg/ml + Human Platelet (Human adult normal cell line) Whole Cell Lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 42 kDa
    Observed band size : 42 kDa


    Exposure time : 5 minutes

References for Anti-Proteinase Activated Receptor 3 antibody (ab66068)

This product has been referenced in:
  • Wang T  et al. Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. J Cell Sci 127:2483-92 (2014). Mouse . Read more (PubMed: 24706948) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab66068.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"