Anti-Proteinase Activated Receptor 3 antibody - C-terminal (ab195797)

Overview

  • Product name
    Anti-Proteinase Activated Receptor 3 antibody - C-terminal
    See all Proteinase Activated Receptor 3 primary antibodies
  • Description
    Rabbit polyclonal to Proteinase Activated Receptor 3 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human Proteinase Activated Receptor 3 (C terminal). 14 amino acid peptide.
    Database link: O00254

  • Positive control
    • Human breast tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab195797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
    • Tissue specificity
      Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family.
    • Post-translational
      modifications
      A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • coagulation factor II (thrombin) receptor-like 2 antibody
      • Coagulation factor II receptor-like 2 antibody
      • F2RL2 antibody
      • PAR 3 antibody
      • PAR-3 antibody
      • PAR3 antibody
      • PAR3_HUMAN antibody
      • protease activated receptor 3 antibody
      • Proteinase-activated receptor 3 antibody
      • thrombin receptor like 2 antibody
      • Thrombin receptor-like 2 antibody
      see all

    Images

    • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human breast tissue labeling Proteinase Activated Receptor 3 with ab195797 at 10 µg/mL.

    References

    ab195797 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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