Overview

  • Product nameAnti-Protocadherin 21 antibody
    See all Protocadherin 21 primary antibodies
  • Description
    Rabbit polyclonal to Protocadherin 21
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (

    GSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDRER

    ) of Human PCDH21 (NP_149091).

  • Positive control
    • Fetal heart lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab108234 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 94 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionPotential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells.
  • Sequence similaritiesContains 6 cadherin domains.
  • Post-translational
    modifications
    Undergoes proteolytic cleavage; produces a soluble 95 kDa N-terminal fragment and a 25 kDa cell-associated C-terminal fragment.
  • Cellular localizationCell membrane. Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cadherin-related family member 1 antibody
    • CDHR1 antibody
    • CDHR1_HUMAN antibody
    • CORD15 antibody
    • DKFZp434A132 antibody
    • KIAA1775 antibody
    • MT protocadherin antibody
    • PCDH 21 antibody
    • PCDH21 antibody
    • PCDH21 protein antibody
    • Photoreceptor cadherin antibody
    • prCAD antibody
    • Protocadherin-21 antibody
    • RP65 antibody
    see all

Anti-Protocadherin 21 antibody images

  • Anti-Protocadherin 21 antibody (ab108234) at 1 µg/ml + Fetal heart lysate at 10 µg

    Predicted band size : 94 kDa

References for Anti-Protocadherin 21 antibody (ab108234)

ab108234 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab108234.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"