Overview

  • Product name
    Anti-Protocadherin 21 antibody
    See all Protocadherin 21 primary antibodies
  • Description
    Mouse polyclonal to Protocadherin 21
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-745 of Human Protocadherin 21 isoform 2 (AAH38799.1, UniProt ID: Q96JP9-2).

  • Positive control
    • Protocadherin 21 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab168220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 82 kDa.

Target

  • Function
    Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells.
  • Sequence similarities
    Contains 6 cadherin domains.
  • Post-translational
    modifications
    Undergoes proteolytic cleavage; produces a soluble 95 kDa N-terminal fragment and a 25 kDa cell-associated C-terminal fragment.
  • Cellular localization
    Cell membrane. Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cadherin-related family member 1 antibody
    • CDHR1 antibody
    • CDHR1_HUMAN antibody
    • CORD15 antibody
    • DKFZp434A132 antibody
    • KIAA1775 antibody
    • MT protocadherin antibody
    • PCDH 21 antibody
    • PCDH21 antibody
    • PCDH21 protein antibody
    • Photoreceptor cadherin antibody
    • prCAD antibody
    • Protocadherin-21 antibody
    • RP65 antibody
    see all

Images

  • All lanes : Anti-Protocadherin 21 antibody (ab168220) at 1 µg/ml

    Lane 1 : Protocadherin 21 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Predicted band size: 82 kDa

References

ab168220 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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