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Rabbit polyclonal to PRPF3
HumanPredicted to work with:
Mouse, Rat, Cow, Dog, Pig
A region within synthetic peptide: VDKLFEAVEE GRSSRHSKSS SDRSRKRELK EVFGDDSEIS KESSGVKKRR, corresponding to amino acids 63-112 of Human PRPF3
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 0.5 µg/ml. Detects a band of approximately 77 kDa (predicted molecular weight: 77 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Titre using peptide based assay 1/62500.
Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain.
Involvement in disease
Retinitis pigmentosa 18
Contains 1 PWI domain.
Nucleus speckle. Colocalizes with spliceosomal snRNPs.
Information by UniProt
- hPrp3 antibody
- HPRP3P antibody
- Pre mRNA splicing factor 3 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"