Overview

  • Product name
  • Description
    Rabbit polyclonal to PRPF4B
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 1 and 50 of Human PRPF4B (NP_003904.3).

  • Positive control
    • Human thyroid and ovarian carcinoma tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab105187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated by Clk1.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • dJ1013A10.1 (PRP4 protein kinase homolog) antibody
    • dJ1013A10.1 antibody
    • KIAA0536 antibody
    • PR4H antibody
    • Protein serine/threonine kinase antibody
    • PRP4 antibody
    • PRP4 kinase antibody
    • PRP4 pre mRNA processing factor 4 homolog antibody
    • PRP4 pre mRNA processing factor 4 homolog B (yeast) antibody
    • PRP4 pre-mRNA-processing factor 4 homolog antibody
    • PRP4B_HUMAN antibody
    • PRP4H antibody
    • PRP4K antibody
    • PRPF4B antibody
    • Serine/threonine protein kinase PRP4 homolog antibody
    • Serine/threonine-protein kinase PRP4 homolog antibody
    see all

Images

  • ab105187 at 1/250 dilution staining PRPF4B in Human thyroid carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
  • ab105187 at 1/250 dilution staining PRPF4B in Human ovarian carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

References

ab105187 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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