Overview

  • Product nameAnti-PSCA antibody, prediluted
    See all PSCA primary antibodies
  • Description
    Rabbit polyclonal to PSCA, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) (extracellular).

  • Positive control
    • Bladder carcinoma and Prostate carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab15169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready to use. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Not tested in other applications.
  • Target

    • RelevancePSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
    • Cellular localizationCell membrane; Lipid-anchor, GPI-anchor.
    • Database links
    • Alternative names
      • PRO 232 antibody
      • PRO232 antibody
      • Prostate stem cell antigen antibody

    Anti-PSCA antibody, prediluted images

    • ab15169 staining PSCA in human breast carcinoma by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    References for Anti-PSCA antibody, prediluted (ab15169)

    This product has been referenced in:
    • Taeb J  et al. Expression of prostate stem cell antigen (PSCA) in prostate cancer: A tissue microarray study of Iranian patients. Pathol Res Pract N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24183365) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"