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Products:Immunology >> Adaptive Immunity >> T Cells >> Non-CD
Overview
Product name
Anti-PSCDBP antibody
See all PSCDBP products (4) ...
Description
Goat polyclonal to PSCDBP
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide: SLQRLLQHSSNGN, corresponding to N terminal amino acids 2-14 of Human PSCDBP.
SLQRLLQHSS NGN-C
Positive control
Jurkat lysate.
General notes
GenBank Accession Number – NP_004279.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> Leucine Zipper
Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> T Cell Adhesion
Immunology >> Adaptive Immunity >> T Cells >> Non-CD
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Western blot - PSCDBP antibody (ab2247)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab2247 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 3 µg/ml.Detects a band of approximately 40 kDa (predicted molecular weight: 41 kDa).
ELISA: 1/16000
Target
Function
By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
Tissue specificity
Expressed in lymph nodes, thymus, spleen, lung, peripheral blood leukocytes and bone marrow.
Sequence similarities
Contains 1 PDZ (DHR) domain.
Cellular localization
Cytoplasm. Early endosome. Recruited from the cytosol to endosomes by SNX27.
Target information above from: UniProt accessionO60759
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- B31 antibody
- CASP antibody
- Cbp HE antibody
see all
Database links
- Entrez Gene: 9595 Human
- Omim: 604448 Human
- SwissProt: O60759 Human
- Unigene: 270 Human
Anti-PSCDBP antibody images:
Western blot - PSCDBP antibody (ab2247)
Predicted band size : 41 kDa
ab2247 staining (1 µg/ml) of MOLT4 cell lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence
References for Anti-PSCDBP antibody (ab2247)
This product has been referenced in:
- O'Brien Met al. Upregulation of PSCDBP, TLR2, TWIST1, FLJ35382, EDNRB, and RGS12 gene expression in human myometrium at labor. Reprod Sci 15:382-93 (2008).Read more (PubMed: 18497345) »
- MacNeil AJet al. Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes. Biochem Biophys Res Commun 359:848-53 (2007). IP; Human.Read more (PubMed: 17577583) »
See all 2 publications for this product
Publishing research using ab2247? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"