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Western blot - PSD95 antibody [6G6-1C9] (ab2723)
![Western blot - PSD95 antibody [6G6-1C9] (ab2723)](/ps/datasheet/images/ab2723_1.jpg)
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Immunocytochemistry/ Immunofluorescence - PSD95 antibody [6G6-1C9] (ab2723)
![Immunocytochemistry/ Immunofluorescence - PSD95 antibody [6G6-1C9] (ab2723)](/ps/datasheet/images/ab2723_2.jpg)
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Product Name
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PSD95 antibody [6G6-1C9]
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See all PSD95 antibodies (12)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [6G6-1C9] to PSD95
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Immunogen
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Purified recombinant rat PSD-95.
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Reacts with
(species key)
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Hu, Ms, Rat, Cow
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Specificity
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Detects Post Synaptic Density 95 kDa (PSD-95) from rat tissues.
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Tested applications
(see key)
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ICC/IF, IHC-Fr, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions ICC/IF: Use at an assay dependent concentration. IF: 1/200. IHC-Fr: 1/1000 (PMID 19038221). WB: 1/2000. Detects a band of approximately ~95-105 kDa.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic
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Research areas
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Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker Neuroscience >> Neurotransmission >> Intracellular Signaling >> Adapters
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Relevance
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PSD95 is a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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6G6-1C9
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Isotype
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IgG2a
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.09% Sodium Azide Constituents: 50% Glycerol, PBS, pH 7.4 Material safety datasheets (MSDS) for this product: Glycerol MSDS Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PSD95 antibody [6G6-1C9] is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for PSD95 antibody [6G6-1C9] images, references, products related to ab2723 and other tools.
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PSD95 antibody [6G6-1C9] images:
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Immunocytochemistry/ Immunofluorescence - PSD95 antibody [6G6-1C9] (ab2723)
ab2723 at 1/200 staining rat primary hippocampal neurons by ICC/IF. The cells were paraformaldehyde fixed and then permeabilized with 0.1% Triton X-100 before being stained with the antibody for 1 hour. An Alexa-Fluor ® 594 conjugated goat polyclonal antibody was used as the secondary. The antibody shows numerous puncta along the shafts. This image is courtesy of an Abreview submitted by Dr Farida Korobova
See Abreview
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References for PSD95 antibody [6G6-1C9] (ab2723)
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This product has been used in: (two most recent references)
Gonalves J et al. Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin. Eur J Neurosci : (2010). WB; Mouse. PubMed: 20074221
Hoon M et al. Neuroligin 2 controls the maturation of GABAergic synapses and information processing in the retina. J Neurosci 29:8039-50 (2009). IHC-Fr; Mouse. PubMed: 19553444
See all 8 publication references for this product.
If you publish research using ab2723 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to PSD95
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PSD95 antibody [6G6-1C9] - more information
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Customer reviews (feedback) regarding PSD95 antibody [6G6-1C9] |
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Price and availability of products related to PSD95 antibody [6G6-1C9] |
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PSD95 antibody [6G6-1C9] - related products:
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PSD95 antibody [6G6-1C9] - other tools:
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Contact Abcam with a Technical Enquiry about PSD95 antibody [6G6-1C9] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"