Overview

  • Product nameAnti-PSF2 antibody
    See all PSF2 primary antibodies
  • Description
    Chicken polyclonal to PSF2
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length native protein (purified) (Human) PSF2

  • Positive control
    • E coli derived fusion protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferAzide free.
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgY
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 21 kDa. We recommend using about 2.5 ug of positive control protein in the colorimetric method, and about 10x less for ECL detection.
ICC/IF Use at an assay dependent dilution. PubMed: 20571081

Target

  • FunctionThe GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
  • Sequence similaritiesBelongs to the GINS2/PSF2 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DNA replication complex GINS protein PSF2 antibody
    • GINS complex subunit 2 (Psf2 homolog) antibody
    • GINS complex subunit 2 antibody
    • gins2 antibody
    • HSPC037 antibody
    • Pfs2 antibody
    • PSF2 antibody
    • PSF2_HUMAN antibody
    see all

Anti-PSF2 antibody images

References for Anti-PSF2 antibody (ab37683)

This product has been referenced in:
  • Tumini E  et al. Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex. DNA Repair (Amst) 10:149-58 (2011). WB ; Human . Read more (PubMed: 21109493) »
  • Cohen SM  et al. BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression. Nucleic Acids Res 38:6906-19 (2010). ICC/IF ; Mouse . Read more (PubMed: 20571081) »

See all 3 Publications for this product

Product Wall

Thank you for your inquiry; the source of this antibody traditionally uses the fusion proteins as testing positive controls, therefore we do not know how the antibody performs on endogenous protein I'm afraid.I can confirm that they have loaded between...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"