Overview

  • Product nameAnti-PSMB5 antibody
    See all PSMB5 primary antibodies
  • Description
    Goat polyclonal to PSMB5
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PSMB5.
    Database link: P28074

  • Positive control
    • Human Brain: cerebellum and cortex tissues

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage throught the Nrf2-ARE pathway.
  • Sequence similaritiesBelongs to the peptidase T1B family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp459C139 antibody
    • EC 3.4.25.1 antibody
    • LMPX antibody
    • Macropain epsilon chain antibody
    • MB1 antibody
    • MGC104214 antibody
    • MGC118075 antibody
    • MGC134464 antibody
    • Multicatalytic endopeptidase complex epsilon chain antibody
    • Proteasome (prosome, macropain) subunit, beta type, 5 antibody
    • Proteasome beta 5 subunit antibody
    • Proteasome catalytic subunit 3 antibody
    • Proteasome chain 6 antibody
    • Proteasome epsilon chain antibody
    • Proteasome subunit beta type-5 antibody
    • Proteasome subunit MB1 antibody
    • Proteasome subunit X antibody
    • Proteasome subunit, beta type, 5 antibody
    • Proteasome subunit, beta-5 antibody
    • PSB5_HUMAN antibody
    • PSMB5 antibody
    • PSX large multifunctional protease X antibody
    • X antibody
    see all

Anti-PSMB5 antibody images

  • Formalin-Fixed, Paraffin-Embedded Human Brain cerebellum tissue stained using ab111263 at a concentration of 3.75 µg/ml.
  • Formalin-Fixed, Paraffin-Embedded Human Brain cortex tissue stained using ab111263 at a concentration of 3.75 µg/ml.

References for Anti-PSMB5 antibody (ab111263)

ab111263 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"