• Product nameAnti-PSMC3IP antibody
    See all PSMC3IP primary antibodies
  • Description
    Rabbit polyclonal to PSMC3IP
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide derived from within residues: PEEKEQVYRE RQKYCKEWRK RKRMATELSD AILEGYPKSK KQFFEEVGIE , corresponding to internal sequence amino acids 143-192 of Human PSMC3IP (NP_037422)

  • Positive control
    • 721_B cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG


Our Abpromise guarantee covers the use of ab82772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/1562500.


  • FunctionPlays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors.
  • Tissue specificityHighly expressed in testis and colon.
  • Involvement in diseaseOvarian dysgenesis 3 (ODG3) [MIM:614324]: A disorder characterized by lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism as a result of streak gonads. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Sequence similaritiesBelongs to the HOP2 family.
  • Post-translational
    PTM: Phosphorylated by PKA, PKC and MAPK.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DBD interacting antibody
    • GT198 antibody
    • Homologous pairing protein 2 homolog antibody
    • Homologous-pairing protein 2 homolog antibody
    • HOP2 antibody
    • HOP2_HUMAN antibody
    • Nuclear receptor coactivator GT198 antibody
    • Proteasome 26S ATPase subunit 3 interacting protein antibody
    • Proteasome 26S ATPase subunit 3-interacting protein antibody
    • PSMC3 interacting protein antibody
    • PSMC3-interacting protein antibody
    • Psmc3ip antibody
    • Tat binding protein 1-interacting protein antibody
    • Tat-binding protein 1-interacting protein antibody
    • TBP-1-interacting protein antibody
    • TBP1 interacting protein antibody
    • TBPIP antibody
    see all

Anti-PSMC3IP antibody images

  • Anti-PSMC3IP antibody (ab82772) at 1 µg/ml + 721_B cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 24 kDa
    Observed band size : 24 kDa
    Additional bands at : 28 kDa,55 kDa. We are unsure as to the identity of these extra bands.

References for Anti-PSMC3IP antibody (ab82772)

ab82772 has not yet been referenced specifically in any publications.

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