FunctionActs as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process.
Tissue specificityExpressed in all tissues tested, highly expressed in liver and kidney.
Sequence similaritiesBelongs to the proteasome subunit p27 family. Contains 1 PDZ (DHR) domain.