The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 15 kDa (predicted molecular weight: 11.5 kDa).
Tissue specificityFetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
Sequence similaritiesBelongs to the S-101 family. Contains 2 EF-hand domains.
Cellular localizationCytoplasm. Secreted. Secreted by a non-classical secretory pathway.