Overview

  • Product nameAnti-PTBP1 antibody
    See all PTBP1 primary antibodies
  • Description
    Mouse monoclonal to PTBP1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: KKFKGDSRSA GVPSRVIHIR KLPIDVTEGE VISLGLPFGK VTNLLMLKGK NQAFIEMNTE EAANTMVNYY TSVTPVLRGQ PIYIQFSNHK ELKTDSSPNQ , corresponding to amino acids 45-145 of Human PTBP1

Properties

Applications

Our Abpromise guarantee covers the use of ab58131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
    • Sequence similaritiesContains 4 RRM (RNA recognition motif) domains.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 57 kDa RNA binding protein PPTB 1 antibody
      • 57 kDa RNA-binding protein PPTB-1 antibody
      • Heterogeneous nuclear ribonucleoprotein I antibody
      • Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody
      • hnRNP I antibody
      • HNRNP-I antibody
      • HNRNPI antibody
      • HNRPI antibody
      • MGC10830 antibody
      • MGC8461 antibody
      • Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody
      • Polypyrimidine Tract Binding Protein 1 antibody
      • Polypyrimidine tract binding protein antibody
      • Polypyrimidine tract-binding protein 1 antibody
      • pPTB antibody
      • PTB 1 antibody
      • PTB 2 antibody
      • PTB 3 antibody
      • PTB 4 antibody
      • PTB antibody
      • PTB T antibody
      • PTB1 antibody
      • PTB2 antibody
      • PTB3 antibody
      • PTB4 antibody
      • PTBP 1 antibody
      • PTBP1 antibody
      • PTBP1_HUMAN antibody
      • PTBT antibody
      • RNA Binding Protein antibody
      see all

    Anti-PTBP1 antibody images

    • PTBP1 antibody (ab58131) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human kidney.


    • Predicted band size : 57 kDa
      PTBP1 antibody (ab58131) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    References for Anti-PTBP1 antibody (ab58131)

    This product has been referenced in:
    • Hope NR & Murray GI The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis. Hum Pathol 42:393-402 (2011). IHC-P ; Human . Read more (PubMed: 21194727) »

    See 1 Publication for this product

    Product Wall

    Thank you for your e-mail. We have not tested the cross reactivity between PTBP1 and PTBP2 or other products yet. We feel sorry that at this moment we have no information about their cross reactivity. Please feel free to contact me if I can provide fu...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"