Validated using a knockout cell line

Anti-PTEN antibody [Y184] (ab32199)

Publishing research using ab32199? Please let us know so that we can cite the reference in this datasheet.

ab32199 has been referenced in 25 publications.

  • Xie Y  et al. Anti-diabetic effect of Alpinia oxyphylla extract on 57BL/KsJ db-/db- mice. Exp Ther Med 13:1321-1328 (2017). WB ; Mouse . PubMed: 28413472
  • Weng M  et al. The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer. Oncotarget 8:20288-20296 (2017). WB ; Human . PubMed: 28423617
  • Ma J  et al. microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury. Am J Transl Res 8:1895-902 (2016). WB ; Rat . PubMed: 27186313
  • Chang H  et al. EGFR protein expression using a specific intracellular domain antibody and PTEN and clinical outcomes in squamous cell lung cancer patients with EGFR-tyrosine kinase inhibitor therapy. Onco Targets Ther 9:5153-62 (2016). IHC ; Human . PubMed: 27578983
  • Gusscott S  et al. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS One 11:e0161158 (2016). WB . PubMed: 27532210
  • He S  et al. Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling. Oncol Lett 11:2223-2228 (2016). Human . PubMed: 26998152
  • Yang J  et al. PREX2 promotes the proliferation, invasion and migration of pancreatic cancer cells by modulating the PI3K signaling pathway. Oncol Lett 12:1139-1143 (2016). WB ; Human . PubMed: 27446408
  • Geng J  et al. Down-regulation of USP13 mediates phenotype transformation of fibroblasts in idiopathic pulmonary fibrosis. Respir Res 16:124 (2015). WB . PubMed: 26453058
  • Li CJ  et al. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest 125:1509-22 (2015). WB ; Mouse . PubMed: 25751060
  • Liao HF  et al. DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells. Development 141:2402-13 (2014). PubMed: 24850856
  • Ngalame NN  et al. Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. Toxicol Sci 138:268-77 (2014). PubMed: 24431212
  • Hammond VE  et al. Ndfip1 Is Required for the Development of Pyramidal Neuron Dendrites and Spines in the Neocortex. Cereb Cortex N/A:N/A (2013). PubMed: 23897647
  • Surviladze Z  et al. Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy. J Virol 87:2508-17 (2013). PubMed: 23255786
  • Kucherlapati MH  et al. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS One 8:e68817 (2013). PubMed: 23935891
  • Xu Y  et al. Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen. Environ Health Perspect 121:944-50 (2013). WB ; Human . PubMed: 23687063
  • Howitt J  et al. Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. J Cell Biol 196:29-36 (2012). PubMed: 22213801
  • Sangale Z  et al. A robust immunohistochemical assay for detecting PTEN expression in human tumors. Appl Immunohistochem Mol Morphol 19:173-83 (2011). PubMed: 20930614
  • Manna P & Jain SK Hydrogen Sulfide and L-Cysteine Increase Phosphatidylinositol 3,4,5-Trisphosphate (PIP3) and Glucose Utilization by Inhibiting Phosphatase and Tensin Homolog (PTEN) Protein and Activating Phosphoinositide 3-Kinase (PI3K)/Serine/Threonine Protein Kinase (AKT)/Protein Kinase C?/? (PKC?/?) in 3T3l1 Adipocytes. J Biol Chem 286:39848-59 (2011). WB ; Mouse . PubMed: 21953448
  • Medyouf H  et al. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss. Blood 115:1175-84 (2010). Flow Cyt ; Human . PubMed: 20008304
  • Akesson E  et al. Prognostic significance of estrogen and progesterone receptor expression in LNG-IUS (Mirena) treatment of endometrial hyperplasia: an immunohistochemical study. Acta Obstet Gynecol Scand 89:393-8 (2010). IHC-P ; Human . PubMed: 20199355
  • Wargon V  et al. Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. Breast Cancer Res Treat : (2010). WB ; Mouse . PubMed: 20440553
  • Vlashi E  et al. Differential Effects of the Proteasome Inhibitor NPI-0052 against Glioma Cells. Transl Oncol 3:50-5 (2010). WB ; Human . PubMed: 20165695
  • Lee DY  et al. Expression of Versican 3'-Untranslated Region Modulates Endogenous MicroRNA Functions. PLoS One 5:e13599 (2010). WB, IHC-P ; Mouse . PubMed: 21049042
  • Diegel CR  et al. Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of apc and pten in the mouse salivary gland: implications for human acinic cell carcinoma. Cancer Res 70:9143-52 (2010). IHC-P ; Mouse . PubMed: 21062985
  • Zeiser R  et al. Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. Blood 111:453-62 (2008). PubMed: 17967941


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