Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab157383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-PTGER3 antibody (ab115667)

  • Purity
    70 - 90% by HPLC.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituent: PBS

General Info

  • Alternative names
    • EP 3
    • EP3
    • EP3 I
    • EP3 II
    • EP3 III
    • EP3 IV
    • Ep3 prostanoid receptor
    • Ep3 receptor
    • EP3 subtype
    • EP3e
    • HGNC:9595
    • MGC141828
    • MGC141829
    • MGC27302
    • PE2R3_HUMAN
    • PGE receptor EP3 subtype
    • PGE2 R
    • PGE2 receptor EP3 subtype
    • PGE2-R
    • PGE2R
    • Pgerep3
    • Prostaglandin E receptor 3
    • Prostaglandin E receptor 3 (subtype EP3)
    • Prostaglandin E receptor EP3 subtype 3 isoform
    • Prostaglandin E2 receptor
    • Prostaglandin e2 receptor ep3
    • Prostaglandin E2 receptor EP3 subtype
    • Prostaglandin receptor (PGE 2)
    • Prostaglandin receptor 3, EP3, subtype
    • Prostanoid EP3 receptor
    • PTGER 3
    • Ptger3
    • Ptgerep3
    • Rep3
    • rEP3a
    • rEP3b
    see all
  • Function
    Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.
  • Tissue specificity
    Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab157383 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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