The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at an assay dependent dilution. Predicted molecular weight: 20 kDa.
With this antibody, we have found that blocking with 5% goat or donkey serum significantly reduces background as compared to BSA or milk.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceParathyroid related protein (PTHLH), is a polypeptide hormone produced by almost every tissue of the body and is closely related to parathyroid hormone (PTH). It signals through its receptor, PTHR1, regulating endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. The receptor for this hormone (PTHRP) is responsible for most cases of humoral hypercalcemia of malignancy.
Cellular localizationCytoplasmic, Nuclear and Secreted