Recombinant Anti-PTP4A2/PRL2 antibody [EPR3800] (ab109118)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3800] to PTP4A2/PRL2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-PTP4A2/PRL2 antibody [EPR3800]
See all PTP4A2/PRL2 primary antibodies -
Description
Rabbit monoclonal [EPR3800] to PTP4A2/PRL2 -
Host species
Rabbit -
Specificity
The immunogen used for this product shares 71% identity (78% positives) with PRL-1. Cross-reactivity with this protein has not been confirmed experimentally.
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Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF or IHC-P -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- WB: SW480, SKBR-3, A549 and HeLa cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR3800 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab109118 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Detects a band of approximately 23 kDa (predicted molecular weight: 19 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 23 kDa (predicted molecular weight: 19 kDa). |
Target
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Relevance
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue. -
Cellular localization
Cell Membrane, Early Endosome and Cytoplasm. -
Database links
- Entrez Gene: 8073 Human
- Entrez Gene: 19244 Mouse
- Entrez Gene: 85237 Rat
- Omim: 601584 Human
- SwissProt: Q12974 Human
- SwissProt: O70274 Mouse
- SwissProt: Q6P9X4 Rat
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Alternative names
- BM 008 antibody
- EC 3.1.3.48 antibody
- HH 13 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab109118 has been referenced in 1 publication.
- Shi L et al. Downregulated Expression of miRNA-130a-5p Aggravates Hepatoma Progression via Targeting PTP4A2. Comput Math Methods Med 2021:4439505 (2021). PubMed: 34992672