Overview

  • Product nameAnti-PTPD2 antibody
    See all PTPD2 primary antibodies
  • Description
    Rabbit polyclonal to PTPD2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within C terminal amino acids 861-890 of Human PTPD2 (Accession: NP_005392.2).

  • Positive control
    • Mouse bladder tissue lysates.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab123729 was purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab123729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 135 kDa.

Target

  • FunctionProtein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis.
  • Tissue specificityExpressed in a variety of human tissues including kidney, skeletal muscle, lung and placenta.
  • Involvement in diseaseDefects in PTPN14 are a cause of choanal atresia and lymphedema (CHATLY) [MIM:613611]. A disease characterized by posterior choanal atresia and lymphedema. Additional features are a high-arched palate, hypoplastic nipples, and mild pectus excavatum. Note=A homozygous deletion in PTPN14 predicted to result in frameshift and premature truncation, has been shown to be the cause of choanal atresia and lymphedema in one family.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 FERM domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cytoskeletal associated protein tyrosine phosphatase antibody
    • MGC126803 antibody
    • PEZ antibody
    • Phosphatase with ezrin domain antibody
    • Protein tyrosine phosphatase non receptor type 14 antibody
    • Protein tyrosine phosphatase pez antibody
    • Protein-tyrosine phosphatase pez antibody
    • PTN14_HUMAN antibody
    • PTP 36 antibody
    • PTP36 antibody
    • PTPD 2 antibody
    • PTPN 14 antibody
    • PTPN14 antibody
    • Tyrosine protein phosphatase non receptor type 14 antibody
    • Tyrosine-protein phosphatase non-receptor type 14 antibody
    see all

Anti-PTPD2 antibody images

  • Anti-PTPD2 antibody (ab123729) at 1/100 dilution + Mouse bladder tissue lysates at 35 µg

    Predicted band size : 135 kDa

References for Anti-PTPD2 antibody (ab123729)

ab123729 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"