Overview

  • Product name
    Anti-PTPIA2 / PTPRN antibody
    See all PTPIA2 / PTPRN primary antibodies
  • Description
    Rabbit polyclonal to PTPIA2 / PTPRN
  • Specificity
    Recognises N terminal.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide (10-30 aa in length) in the region of 134~150 of Human PTPIA2/PTPRN.

  • Positive control
    • C6 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab37523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Detects a band of approximately 111 kDa (predicted molecular weight: 111 kDa).
ELISA 1/1000.

Target

  • Function
    Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
  • Tissue specificity
    Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications
    Appears to undergo multiple proteolytic cleavage at consecutive basic residues.
  • Cellular localization
    Membrane. Neuroendocrine secretory granules.
  • Information by UniProt
  • Database links
  • Alternative names
    • CA 512 antibody
    • FLJ16131 antibody
    • IA 2 antibody
    • IA 2/PTP antibody
    • IA2 antibody
    • IA2/PTP antibody
    • ICA 3 antibody
    • ICA 512 antibody
    • ICA3 antibody
    • ICA512 antibody
    • Islet cell antigen 2 antibody
    • Islet cell antigen 512 antibody
    • Islet cell autoantigen 3 antibody
    • Protein tyrosine phosphatase like N antibody
    • Protein tyrosine phosphatase like N precursor antibody
    • Protein tyrosine phosphatase receptor type N antibody
    • PTP IA 2 antibody
    • PTP IA-2 antibody
    • PTP IA2 antibody
    • PTPIA 2 antibody
    • PTPN antibody
    • Ptprn antibody
    • PTPRN protein antibody
    • PTPRN_HUMAN antibody
    • R PTP N antibody
    • R-PTP-N antibody
    • Receptor type tyrosine protein phosphatase like N antibody
    • Receptor-type tyrosine-protein phosphatase-like N antibody
    • RPTPN antibody
    see all

Images

  • Anti-PTPIA2 / PTPRN antibody (ab37523) at 1/100 dilution + C6 cell lysate

    Predicted band size : 111 kDa
    Observed band size : 111 kDa

References

ab37523 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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