Overview

  • Product name
    Anti-PTPIA2 / PTPRN antibody
    See all PTPIA2 / PTPRN primary antibodies
  • Description
    Goat polyclonal to PTPIA2 / PTPRN
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Cow, Dog, Human, Chimpanzee, Orangutan
  • Immunogen

    Synthetic peptide:

    QGEGNIKKNRHPD

    , corresponding to internal sequence amino acids 730-742 of Human PTPIA2/ PTPRN (NP_002837.1)

  • Positive control
    • NIH3T3 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab77409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/16000.
    WB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 106 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
    • Tissue specificity
      Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
    • Sequence similarities
      Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
      Contains 1 tyrosine-protein phosphatase domain.
    • Post-translational
      modifications
      Appears to undergo multiple proteolytic cleavage at consecutive basic residues.
    • Cellular localization
      Membrane. Neuroendocrine secretory granules.
    • Information by UniProt
    • Database links
    • Alternative names
      • CA 512 antibody
      • FLJ16131 antibody
      • IA 2 antibody
      • IA 2/PTP antibody
      • IA2 antibody
      • IA2/PTP antibody
      • ICA 3 antibody
      • ICA 512 antibody
      • ICA3 antibody
      • ICA512 antibody
      • Islet cell antigen 2 antibody
      • Islet cell antigen 512 antibody
      • Islet cell autoantigen 3 antibody
      • Protein tyrosine phosphatase like N antibody
      • Protein tyrosine phosphatase like N precursor antibody
      • Protein tyrosine phosphatase receptor type N antibody
      • PTP IA 2 antibody
      • PTP IA-2 antibody
      • PTP IA2 antibody
      • PTPIA 2 antibody
      • PTPN antibody
      • Ptprn antibody
      • PTPRN protein antibody
      • PTPRN_HUMAN antibody
      • R PTP N antibody
      • R-PTP-N antibody
      • Receptor type tyrosine protein phosphatase like N antibody
      • Receptor-type tyrosine-protein phosphatase-like N antibody
      • RPTPN antibody
      see all

    Images

    References

    ab77409 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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