Anti-PTPIA2 / PTPRN antibody [AFT38] (ab75525)

Overview

  • Product nameAnti-PTPIA2 / PTPRN antibody [AFT38]
    See all PTPIA2 / PTPRN primary antibodies
  • Description
    Mouse monoclonal [AFT38] to PTPIA2 / PTPRN
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human PTPIA2/ PTPRN protein purified from E. coli

  • Positive control
    • Bosc23 cell lysate transfected with Myc/His/PTPIA2 / PTPRN.

Properties

Applications

Our Abpromise guarantee covers the use of ab75525 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 106 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionImplicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
  • Tissue specificityExpression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications
    Appears to undergo multiple proteolytic cleavage at consecutive basic residues.
  • Cellular localizationMembrane. Neuroendocrine secretory granules.
  • Information by UniProt
  • Database links
  • Alternative names
    • CA 512 antibody
    • FLJ16131 antibody
    • IA 2 antibody
    • IA 2/PTP antibody
    • IA2 antibody
    • IA2/PTP antibody
    • ICA 3 antibody
    • ICA 512 antibody
    • ICA3 antibody
    • ICA512 antibody
    • Islet cell antigen 2 antibody
    • Islet cell antigen 512 antibody
    • Islet cell autoantigen 3 antibody
    • Protein tyrosine phosphatase like N antibody
    • Protein tyrosine phosphatase like N precursor antibody
    • Protein tyrosine phosphatase receptor type N antibody
    • PTP IA 2 antibody
    • PTP IA-2 antibody
    • PTP IA2 antibody
    • PTPIA 2 antibody
    • PTPN antibody
    • Ptprn antibody
    • PTPRN protein antibody
    • PTPRN_HUMAN antibody
    • R PTP N antibody
    • R-PTP-N antibody
    • Receptor type tyrosine protein phosphatase like N antibody
    • Receptor-type tyrosine-protein phosphatase-like N antibody
    • RPTPN antibody
    see all

References for Anti-PTPIA2 / PTPRN antibody [AFT38] (ab75525)

ab75525 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam. I have asked the lab for the concentration of ab75525 and they have told me that the concentration of this product is unknown. It is assumed that the concentration of the total protein for ab75525 is 0.5~2 mg per 1ml con...

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Thank you for contacting us. The antibody binds in the general region of a.a. 709 - 979 (see WB attached, lane 3). I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"