The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
RelevancePTPLAD1 is a component of Rac1-signaling pathways leading to the modulation of gene expression. It potentiates different effects of the small GTPase Rac1, such as c-Jun N-terminal kinase activation and transcriptional activity of nuclear factor kappaB (NF-kappaB).It plays a crucial role in HCV RNA replication and the propagation of JFH1 virus through interaction with viral and host proteins.
Cellular localizationMembrane; Multi-pass membrane protein