The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
RelevancePTPLAD1 is a component of Rac1-signaling pathways leading to the modulation of gene expression. It potentiates different effects of the small GTPase Rac1, such as c-Jun N-terminal kinase activation and transcriptional activity of nuclear factor kappaB (NF-kappaB).It plays a crucial role in HCV RNA replication and the propagation of JFH1 virus through interaction with viral and host proteins.
Cellular localizationMembrane; Multi-pass membrane protein