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Overview

  • Product name
    Anti-PU.1/Spi1 antibody
    See all PU.1/Spi1 primary antibodies
  • Description
    Goat polyclonal to PU.1/Spi1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide to Human PU.1/Spi1

  • Positive control
    • Human Colon lymphoid aggregate and Human Spleen tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab111002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
  • Sequence similarities
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • transcription factor spi1 antibody
      • 31 kDa Transforming Protein antibody
      • 31 kDa-transforming protein antibody
      • cb1086 antibody
      • Hematopoietic transcription factor PU.1 antibody
      • OF antibody
      • oncogene spi1 antibody
      • PU.1 antibody
      • SFFV virus-induced murine erythroleukemia oncogene, mouse, homolog of antibody
      • SFPI1 antibody
      • si:by184l24.2 antibody
      • SPI 1 antibody
      • SPI 1 proto oncogene antibody
      • SPI A antibody
      • Spi1 antibody
      • SPI1_HUMAN antibody
      • Spleen focus forming virus (SFFV) proviral integration oncogene spi1 antibody
      • Spleen focus forming virus proviral integration oncogene spi1 antibody
      • Transcription factor PU.1 antibody
      see all

    Anti-PU.1/Spi1 antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      ab111002, at 3.75µg/ml, staining PU.1/Spi1 in formalin-fixed, paraffin-embedded Human Colon lymphoid aggregate by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      ab111002, at 3.75µg/ml, staining PU.1/Spi1 in formalin-fixed, paraffin-embedded Human Spleen tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

    References for Anti-PU.1/Spi1 antibody (ab111002)

    ab111002 has not yet been referenced specifically in any publications.

    Publishing research using ab111002? Please let us know so that we can cite the reference in this datasheet.

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