Overview

  • Product name
    Anti-PU.1/Spi1 antibody
    See all PU.1/Spi1 primary antibodies
  • Description
    Goat polyclonal to PU.1/Spi1
  • Host species
    Goat
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide to Human PU.1/Spi1

  • Positive control
    • Human Colon lymphoid aggregate and Human Spleen tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab111002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
  • Sequence similarities
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • transcription factor spi1 antibody
      • 31 kDa Transforming Protein antibody
      • 31 kDa-transforming protein antibody
      • cb1086 antibody
      • Hematopoietic transcription factor PU.1 antibody
      • OF antibody
      • oncogene spi1 antibody
      • PU.1 antibody
      • SFFV virus-induced murine erythroleukemia oncogene, mouse, homolog of antibody
      • SFPI1 antibody
      • si:by184l24.2 antibody
      • SPI 1 antibody
      • SPI 1 proto oncogene antibody
      • SPI A antibody
      • Spi1 antibody
      • SPI1_HUMAN antibody
      • Spleen focus forming virus (SFFV) proviral integration oncogene spi1 antibody
      • Spleen focus forming virus proviral integration oncogene spi1 antibody
      • Transcription factor PU.1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      ab111002, at 3.75µg/ml, staining PU.1/Spi1 in formalin-fixed, paraffin-embedded Human Colon lymphoid aggregate by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PU.1/Spi1 antibody (ab111002)
      ab111002, at 3.75µg/ml, staining PU.1/Spi1 in formalin-fixed, paraffin-embedded Human Spleen tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

    References

    ab111002 has not yet been referenced specifically in any publications.

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