Overview

  • Product nameAnti-PYGL antibody
    See all PYGL primary antibodies
  • Description
    Rabbit polyclonal to PYGL
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human PYGL (NP_002854.3, amino acids 1-847).

  • Positive control
    • Human liver tissue lysate; PYGL transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 97 kDa.

Target

  • FunctionPhosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • Involvement in diseaseDefects in PYGL are the cause of glycogen storage disease type 6 (GSD6) [MIM:232700]. A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected.
  • Sequence similaritiesBelongs to the glycogen phosphorylase family.
  • Post-translational
    modifications
    Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glycogen phosphorylase antibody
    • Glycogen phosphorylase liver antibody
    • Glycogen phosphorylase liver form antibody
    • GSD6 antibody
    • Hers disease, glycogen storage disease type VI antibody
    • liver form antibody
    • OTTHUMP00000233649 antibody
    • OTTHUMP00000233651 antibody
    • Phosphorylase glycogen liver antibody
    • Pygl antibody
    • PYGL_HUMAN antibody
    see all

Anti-PYGL antibody images

  • Anti-PYGL antibody (ab103419) at 5 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 97 kDa
  • All lanes : Anti-PYGL antibody (ab103419) at 5 µg/ml

    Lane 1 : PYGL transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 97 kDa

References for Anti-PYGL antibody (ab103419)

ab103419 has not yet been referenced specifically in any publications.

Product Wall

The PYGL antibody ab103419 is raised against the full-length protein, amino acids 1-847. The sequence is described in the UniProt entry, accession P06737. Here is a link to the entry. http://www.uniprot.org/uniprot/P06737.

It is a polyclonal a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"