Anti-Pyruvate Dehydrogenase E1-alpha subunit antibody [8D10E6] (ab110334)

Publishing research using ab110334? Please let us know so that we can cite the reference in this datasheet.

ab110334 has been referenced in 28 publications.

  • Geiszler PC  et al. Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons. Sci Rep 8:4833 (2018). PubMed: 29555943
  • Yamano K  et al. Endosomal Rab cycles regulate Parkin-mediated mitophagy. Elife 7:N/A (2018). PubMed: 29360040
  • Liu X  et al. Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts. Sci Rep 7:8474 (2017). WB ; Human . PubMed: 28814762
  • Moretton A  et al. Selective mitochondrial DNA degradation following double-strand breaks. PLoS One 12:e0176795 (2017). WB . PubMed: 28453550
  • Jiang YF  et al. Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging. Sci Rep 7:45474 (2017). WB . PubMed: 28358017
  • Nakazawa M  et al. Physiological functions of pyruvate:NADP(+) oxidoreductase and 2-oxoglutarate decarboxylase in Euglena gracilis under aerobic and anaerobic conditions. Biosci Biotechnol Biochem 81:1386-1393 (2017). WB . PubMed: 28463550
  • Desseille C  et al. Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice. Front Mol Neurosci 10:332 (2017). PubMed: 29104532
  • Barquissau V  et al. White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways. Mol Metab 5:352-65 (2016). PubMed: 27110487
  • Li Y  et al. PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence. Oncotarget 7:53837-53852 (2016). PubMed: 27462778
  • Zhu G  et al. Acute effect of lactic acid on tumor-endothelial cell metabolic coupling in the tumor microenvironment. Oncol Lett 12:3478-3484 (2016). WB ; Human . PubMed: 27900024
  • Zhang Z  et al. BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes. EMBO J 35:208-36 (2016). WB . PubMed: 26702098
  • Xu XD  et al. The study of energy metabolism in bladder cancer cells in co-culture conditions using a microfluidic chip. Int J Clin Exp Med 8:12327-36 (2015). PubMed: 26550142
  • Teixeira FK  et al. ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation. Nat Cell Biol 17:689-96 (2015). PubMed: 25915123
  • Tomilov A  et al. Shc depletion stimulates brown fat activity in vivo and in vitro. Aging Cell 13:1049-58 (2014). Mouse . PubMed: 25257068
  • Roselló-Lletí E  et al. Heart mitochondrial proteome study elucidates changes in cardiac energy metabolism and antioxidant PRDX3 in human dilated cardiomyopathy. PLoS One 9:e112971 (2014). WB ; Human . PubMed: 25397948
  • Davoudi M  et al. Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive complex III deficiency. PLoS One 9:e86767 (2014). WB ; Mouse . PubMed: 24466228
  • Caro-Maldonado A  et al. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol 192:3626-36 (2014). PubMed: 24616478
  • Thomas RE  et al. PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix. PLoS Genet 10:e1004279 (2014). WB ; Drosophila melanogaster . PubMed: 24874806
  • Hiniker A  et al. Axial mitochondrial myopathy in a patient with rapidly progressive adult-onset scoliosis. Acta Neuropathol Commun 2:137 (2014). IHC-Fr ; Human . PubMed: 25223649
  • Jin SM & Youle RJ The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 9:1750-7 (2013). WB . PubMed: 24149988
  • Cirillo F  et al. Molecular Mechanisms of Selective Estrogen Receptor Modulator Activity in Human Breast Cancer Cells: Identification of Novel Nuclear Cofactors of Antiestrogen-ERa Complexes by Interaction Proteomics. J Proteome Res : (2012). WB . PubMed: 23170835
  • Ye F  et al. Peroxisome proliferator-activated receptor ? (PPAR?) mediates a Ski oncogene-induced shift from glycolysis to oxidative energy metabolism. J Biol Chem 286:40013-24 (2011). WB . PubMed: 21917928
  • Brys K  et al. Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans. BMC Biol 8:91 (2010). PubMed: 20584279
  • Ostergaard E  et al. Four novel PDHA1 mutations in pyruvate dehydrogenase deficiency. J Inherit Metab Dis : (2009). PubMed: 19517265
  • Glushakova LG  et al. AAV3-mediated transfer and expression of the pyruvate dehydrogenase E1 alpha subunit gene causes metabolic remodeling and apoptosis of human liver cancer cells. Mol Genet Metab 98:289-99 (2009). PubMed: 19586787
  • Cox RT & Spradling AC Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin. Dis Model Mech 2:490-9 (2009). PubMed: 19638420
  • Stenson BM  et al. Activation of liver X receptor regulates substrate oxidation in white adipocytes. Endocrinology 150:4104-13 (2009). PubMed: 19556420
  • Greiss S  et al. C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis. Genes Dev 22:2831-42 (2008). PubMed: 18923081


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