Anti-Pyruvate Dehydrogenase E1-alpha subunit antibody [9H9AF5] (ab110330)

Publishing research using ab110330? Please let us know so that we can cite the reference in this datasheet.

ab110330 has been referenced in 32 publications.

  • McLelland GL  et al. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife 7:N/A (2018). PubMed: 29676259
  • Schatton D  et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-693 (2017). WB ; Mouse . PubMed: 28188211
  • Wang H  et al. Embryonic lethal abnormal vision proteins and adenine and uridine-rich element mRNAs after global cerebral ischemia and reperfusion in the rat. J Cereb Blood Flow Metab 37:1494-1507 (2017). Rat . PubMed: 27381823
  • Ward NP  et al. Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells. PLoS One 12:e0180061 (2017). WB . PubMed: 28644886
  • Zhang Y  et al. Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia. Oncotarget 8:15205-15212 (2017). PubMed: 28148899
  • Vysochan A  et al. ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection. Proc Natl Acad Sci U S A 114:E1528-E1535 (2017). PubMed: 28167750
  • Piao L  et al. Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest. PLoS One 12:e0185046 (2017). WB ; Mouse . PubMed: 28934276
  • Ahn E  et al. Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle. Mol Syst Biol 13:953 (2017). PubMed: 29109155
  • Zhang Y  et al. Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function. PLoS One 11:e0150454 (2016). Mouse . PubMed: 26930489
  • Vavrova E  et al. Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance. Am J Physiol Endocrinol Metab 311:E649-60 (2016). PubMed: 27507552
  • Golias T  et al. Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours. Sci Rep 6:31146 (2016). WB ; Human . PubMed: 27498883
  • Murphy S  et al. Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy. Biology (Basel) 4:397-423 (2015). PubMed: 26067837
  • Buzelle SL  et al. The contribution of IL-6 to beta 3 adrenergic receptor mediated adipose tissue remodeling. Physiol Rep 3:N/A (2015). Mouse . PubMed: 25713332
  • Podobed P  et al. The day/night proteome in the murine heart. Am J Physiol Regul Integr Comp Physiol 307:R121-37 (2014). PubMed: 24789993
  • Hamabe A  et al. Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1a in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis. Cancer Sci 105:1100-8 (2014). IHC . PubMed: 25060325
  • McLelland GL  et al. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J 33:282-95 (2014). PubMed: 24446486
  • Tso SC  et al. Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket. J Biol Chem 289:4432-43 (2014). WB . PubMed: 24356970
  • Ritchie IR  et al. Adiponectin is sufficient, but not required, for exercise-induced increases in the expression of skeletal muscle mitochondrial enzymes. J Physiol 592:2653-65 (2014). WB ; Mouse . PubMed: 24687585
  • Gao J  et al. CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins. J Cell Biol 207:213-23 (2014). PubMed: 25349259
  • Mennes E  et al. Aging-Associated Reductions in Lipolytic and Mitochondrial Proteins in Mouse Adipose Tissue Are Not Rescued by Metformin Treatment. J Gerontol A Biol Sci Med Sci N/A:N/A (2013). Mouse . PubMed: 24127429
  • Xing G  et al. Impact of repeated stress on traumatic brain injury-induced mitochondrial electron transport chain expression and behavioral responses in rats. Front Neurol 4:196 (2013). WB ; Rat . PubMed: 24376434
  • Schilling B  et al. Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation. Mol Cell Proteomics 11:202-14 (2012). WB . PubMed: 22454539
  • Frier BC  et al. Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms. Am J Physiol Regul Integr Comp Physiol 300:R212-21 (2011). PubMed: 21084676
  • Johnson F & Kaplitt MG Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. PLoS One 4:e7100 (2009). PubMed: 19763263
  • Rardin MJ  et al. Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem 389:157-64 (2009). PubMed: 19341700
  • Zhou Q  et al. Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging. FEBS Lett 583:1132-40 (2009). PubMed: 19272379
  • Missihoun C  et al. Myocardial oxidative stress, osteogenic phenotype, and energy metabolism are differentially involved in the initiation and early progression of delta-sarcoglycan-null cardiomyopathy. Mol Cell Biochem 321:45-52 (2009). PubMed: 18726675
  • Han Z  et al. A combined therapeutic approach for pyruvate dehydrogenase deficiency using self-complementary adeno-associated virus serotype-specific vectors and dichloroacetate. Mol Genet Metab 93:381-7 (2008). PubMed: 18206410
  • Zhou Q  et al. c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons. J Neurochem 104:325-35 (2008). PubMed: 17949412
  • Margineantu DH  et al. Hsp90 inhibition decreases mitochondrial protein turnover. PLoS One 2:e1066 (2007). PubMed: 17957250
  • Watson PA  et al. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol 293:H246-59 (2007). PubMed: 17337597
  • Kumar V  et al. Activity of pyruvate dehydrogenase A (PDHA) in hamster spermatozoa correlates positively with hyperactivation and is associated with sperm capacitation. Biol Reprod 75:767-77 (2006). PubMed: 16855207


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