Pyruvate dehydrogenase (PDH) Enzyme Activity Microplate Assay Kit (ab109902)

Publishing research using ab109902? Please let us know so that we can cite the reference in this datasheet.

ab109902 has been referenced in 24 publications.

  • Nguyen QL  et al. Platelets from pulmonary hypertension patients show increased mitochondrial reserve capacity. JCI Insight 2:e91415 (2017). PubMed: 28289721
  • Zhang Y  et al. Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function. PLoS One 11:e0150454 (2016). Functional Studies ; Mouse . PubMed: 26930489
  • Golias T  et al. Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours. Sci Rep 6:31146 (2016). PubMed: 27498883
  • Bround MJ  et al. Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase. J Biol Chem 291:23490-23505 (2016). PubMed: 27621312
  • Sun J  et al. Induction of triglyceride accumulation and mitochondrial maintenance in muscle cells by lactate. Sci Rep 6:33732 (2016). Functional Studies . PubMed: 27645401
  • Shanmughapriya S  et al. Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Sci Signal 8:ra23 (2015). Functional Studies . PubMed: 25737585
  • Prabhu A  et al. Cysteine catabolism: a novel metabolic pathway contributing to glioblastoma growth. Cancer Res 74:787-96 (2014). Functional Studies ; Human . PubMed: 24351290
  • Yamane K  et al. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza. PLoS One 9:e98032 (2014). Functional Studies . PubMed: 24865588
  • Sheriff S  et al. Des-acyl-ghrelin (DAG) normalizes hyperlactacidemia and improves survival in a lethal rat model of burn trauma. Peptides 60:1-7 (2014). Rat . PubMed: 25063053
  • Hamabe A  et al. Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1a in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis. Cancer Sci 105:1100-8 (2014). PubMed: 25060325
  • van der Veen JN  et al. The concentration of phosphatidylethanolamine in mitochondria can modulate ATP production and glucose metabolism in mice. Diabetes 63:2620-30 (2014). Mouse . PubMed: 24677714
  • Kageyama Y  et al. Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. EMBO J 33:2798-813 (2014). PubMed: 25349190
  • Morten KJ  et al. Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts. J Pathol 229:755-64 (2013). PubMed: 23303559
  • Phillips BE  et al. Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study. J Cachexia Sarcopenia Muscle 4:71-7 (2013). Functional Studies ; Human . PubMed: 22648738
  • Geng X  et al. Synergetic neuroprotection of normobaric oxygenation and ethanol in ischemic stroke through improved oxidative mechanism. Stroke 44:1418-25 (2013). PubMed: 23512978
  • Gu F  et al. Alterations in mitochondrial DNA copy number and the activities of electron transport chain complexes and pyruvate dehydrogenase in the frontal cortex from subjects with autism. Transl Psychiatry 3:e299 (2013). PubMed: 24002085
  • Jing E  et al. Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation. Diabetes 62:3404-17 (2013). PubMed: 23835326
  • Ota A  et al. Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells. J Neural Transm : (2012). PubMed: 22392058
  • Thomas SN  et al. Quantitative proteomic analysis of mitochondrial proteins reveals prosurvival mechanisms in the perpetuation of radiation-induced genomic instability. Free Radic Biol Med 53:618-28 (2012). PubMed: 22569412
  • Hong JK  et al. Growth factor withdrawal in combination with sodium butyrate addition extends culture longevity and enhances antibody production in CHO cells. J Biotechnol 155:225-31 (2011). Chinese hamster . PubMed: 21723342
  • Yi X  et al. Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice. Atherosclerosis 211:424-30 (2010). PubMed: 20347443
  • Puthanveetil P  et al. The increase in cardiac pyruvate dehydrogenase kinase-4 after short-term dexamethasone is controlled by an Akt-p38-forkhead box other factor-1 signaling axis. Endocrinology 151:2306-18 (2010). PubMed: 20181797
  • Lee DW  et al. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. J Biol Chem 284:29065-76 (2009). PubMed: 19679656
  • Sikder D & Kodadek T The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. Genes Dev 21:2995-3005 (2007). PubMed: 18006690


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