• Product name
    Anti-Pyruvate Kinase antibody
    See all Pyruvate Kinase primary antibodies
  • Description
    Goat polyclonal to Pyruvate Kinase
  • Host species
  • Specificity
    Recognizes all forms of Pyruvate Kinase.
  • Tested applications
    Suitable for: WB, IP, IHC-P, Flow Cyt, Dot blot, Conjugationmore details
  • Species reactivity
    Reacts with: Rabbit
    Predicted to work with: Human
  • Immunogen

    Pyruvate Kinase from rabbit muscle.

  • Positive control
    • Human Pancreas



Our Abpromise guarantee covers the use of ab118499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 62 kDa.
IP Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt Use at an assay dependent concentration.

ab37373 - Goat polyclonal IgG, is suitable for use as an isotype control with this antibody.


Dot blot Use at an assay dependent concentration.
Conjugation Use at an assay dependent concentration.


  • Relevance
    Pyruvate kinase is also known as ATP:pyruvate phosphotransferase. There are 4 isoforms of piruvate kinase in mammals: L, R, M1 and M2. L type is the major isoform in the liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells. Defects in PKLR (pyruvate kinase L and R) are the cause of pyruvate kinase hyperactivity; also known as high red cell ATP syndrome. This autosomal dominant phenotype is characterized by increase of red blood cell ATP. Also defects in PKLR are a cause of chronic nonspherocytic hemolytic anemia (CNSHA); also called hereditary nonspherocytic hemolytic anemia.
  • Cellular localization
  • Database links
  • Alternative names
    • Pyruvate kinase 3 antibody
    • CTHBP antibody
    • Cytosolic thyroid hormone-binding protein antibody
    • epididymis secretory protein Li 30 antibody
    • HEL-S-30 antibody
    • OIP3 antibody
    • OPA interacting protein 3 antibody
    • p58 antibody
    • PK, muscle type antibody
    • PK1 antibody
    • PK2 antibody
    • PKL antibody
    • PKLR antibody
    • PKM 2 antibody
    • PKM antibody
    • PKM2 antibody
    • PYKM antibody
    • Pyruvate kinase 1 antibody
    • Pyruvate kinase 2/3 antibody
    • Pyruvate kinase isozyme R/L antibody
    • pyruvate kinase isozymes L/R antibody
    • Pyruvate kinase isozymes M1/M2 antibody
    • pyruvate kinase isozymes R/L antibody
    • Pyruvate kinase liver and blood cell antibody
    • Pyruvate kinase liver and RBC antibody
    • Pyruvate kinase muscle antibody
    • Pyruvate kinase muscle isozyme antibody
    • pyruvate kinase PKM antibody
    • pyruvate kinase type L antibody
    • Pyruvate kinase, liver and red blood cell antibody
    • Pyruvate kinase, liver type antibody
    • Pyruvate kinase, muscle, 2 antibody
    • Pyruvate kinase, red cell type antibody
    • R type/L type pyruvate kinase antibody
    • Red cell/liver pyruvate kinase antibody
    • RPK antibody
    • TCB antibody
    • THBP1 antibody
    • Thyroid hormone binding protein cytosolic antibody
    • thyroid hormone-binding protein 1 antibody
    • tumor M2-PK antibody
    see all


  • ab118499 at 5 µg/ml staining Pyruvate Kinase in Human Pancreas by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.


ab118499 has not yet been referenced specifically in any publications.

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