• Product nameAnti-QRX antibody
    See all QRX primary antibodies
  • Description
    Rabbit polyclonal to QRX
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Chimpanzee
  • Immunogen

    Synthetic peptide: MFLSPGEGPA TEGGGLGPGE EAPKKKHRRN RTTFTTYQLH QLERAFEASH, corresponding to amino acids 1-50 of Human QRX

  • Positive control
    • Jurkat cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products


Our Abpromise guarantee covers the use of ab49371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 20 kDa).Can be blocked with QRX peptide (ab129052). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay was 1:312500.


  • FunctionMay be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter.
  • Involvement in diseaseDefects in RAX2 are the cause of age-related macular degeneration type 6 (ARMD6) [MIM:613757]. ARMD is in most patients manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders.
    Defects in RAX2 are the cause of cone-rod dystrophy type 11 (CORD11) [MIM:610381]. CORD is characterized by the initial degeneration of cone photoreceptor cells, thus causing early loss of visual acuity and color vision, followed by the degeneration of rod photoreceptor cells and leading to progressive night blindness and peripheral visual field loss.
  • Sequence similaritiesContains 1 homeobox DNA-binding domain.
  • DomainThe Homeobox transactivates the Ret-1 element in the presence of CRX and NRL.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARMD6 antibody
    • CORD11 antibody
    • Macular degeneration, age related 6, included antibody
    • MGC15631 antibody
    • Q50 type retinal homeobox antibody
    • Q50-type retinal homeobox protein antibody
    • QRX antibody
    • rax2 antibody
    • RAX2_HUMAN antibody
    • RAXL1 antibody
    • Retina and anterior neural fold homeobox like 1 antibody
    • Retina and anterior neural fold homeobox protein 2 antibody
    • Retina and anterior neural fold homeobox-like protein 1 antibody
    see all

Anti-QRX antibody images

  • Anti-QRX antibody (ab49371) at 1.25 µg/ml + Jurkat cell lysate at 10 µg with 5% skim milk in PBS.

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 20 kDa
    Observed band size : 21 kDa (why is the actual band size different from the predicted?)

References for Anti-QRX antibody (ab49371)

ab49371 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your patience. My colleague has added the following peptides to our catalog:

ForRAX2 (QRX), the peptide ab129052 can be used with the antibody ab49371.

For Lhx2, the peptide ab129053 can be used with the antibody ab489...

Read More