The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceQuinolones and fluoroquinolones form a group of broad-spectrum antibiotics. They are related to nalidixic acid.
Fluoroquinolone antibiotics are highly potent and at one time they were considered relatively safe. However, they can have potentially troublesome and irreversable side effects.
Quinolones act by inhibiting the bacterial DNA gyrase and/or the topoisomerase IV enzyme. This way they inhibit DNA replication and act bacteriocidically. As such they are to be considered a chemotherapeutic agent as opposed to a true antibiotic as they prevent replication of the bacterial cell by interfering with the genetic replication of the bacterium.
References for Anti-Quinolone antibody (ab31123)
has not yet been referenced specifically in any publications.
Publishing research using ab31123? Please let us know so that we can cite the reference in this datasheet.
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