Biological description5-HT receptor agonist, shows some selectivity at 5-HT3 (EC50 = 24 nM). Displays antidepressant and anorectic effect. Also promotes cellular proliferation.
Chemical name2-(1-Piperazinyl)quinoline dimaleate
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Liu Y & Zhang ZY Serotonin receptor agonist quipazine promotes proliferation and apoptosis of human hepatocyte strain of L-02 strain. Hepatobiliary Pancreat Dis Int8:278-81 (2009).
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Dubin AE et al. The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit. J Biol Chem274:30799-810 (1999).
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