QVD-OPh Negative control (DMSO solution) (ab146603)

Overview

  • Product name
    QVD-OPh Negative control (DMSO solution)
  • Description
    Negative control for potent broad spectrum caspase inhibitor
  • Biological description
    Negative control for potent broad spectrum caspase inhibitor. Q-VD-OPh (ab141421) negative control. Active in vitro and in vivo. Blood-brain barrier permeable.


    Also available as a solid (ab141389).
  • Purity
    > 95%

Properties

  • Chemical name
    Quinolyl-Val-Glu-OPh
  • Molecular weight
    527.19
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C27H27F2N3O6
  • Storage instructions
    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview
    Supplied in DMSO (10 mM)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    Fc3cccc(F)c3OCC(=O)C(CCC(=O)O)NC(=O)C(NC(=O)c1ccc2ccccc2n1)C(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Lim EJ  et al. Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis. J Gen Virol 95:2204-15 (2014). Read more (PubMed: 24973240) »
  • Patil K & Sharma SC Broad spectrum caspase inhibitor rescues retinal ganglion cells after ischemia. Neuroreport 15:981-4 (2004). Read more (PubMed: 15076719) »
  • Caserta TM  et al. Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties. Apoptosis 8:345-52 (2003). Read more (PubMed: 12815277) »
  • Yin XM Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways. Cell Res 10:161-7 (2000). Read more (PubMed: 11032168) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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