Biological descriptionα1 Adrenoceptor agonist. pKi values are 4.87, 4.70 and 5.86 for adrenoceptor subtypes α1B, α1C and α1A/D, respectively. Vasoconstrictor. Active in vivo, may cross the blood-brain barrier.
Chemical name(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
Storage instructionsStore at Room Temperature. Store under Desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
References for (R)-(-)-Phenylephrine hydrochloride (ab120761)
This product has been referenced in:
Gadek-Michalska A et al. Prostaglandins and interleukin-1beta in the hypothalamic-pituitary-adrenal response to systemic phenylephrine under basal and stress conditions. J Physiol Pharmacol59:563-75 (2008).
Read more (PubMed: 18953098) »
Eccles R Substitution of phenylephrine for pseudoephedrine as a nasal decongeststant. An illogical way to control methamphetamine abuse. Br J Clin Pharmacol63:10-4 (2007).
Read more (PubMed: 17116124) »